The research groups within the Center for Molecular Medicine are at the forefront of investigating neurodegenerative disorders, with a focus on Parkinson's disease and multiple system atrophy. Our mission is to gain deeper insights into the underlying mechanisms of neurodegenerative disorders and to develop new therapeutic interventions.
As part of these multidisciplinary research groups, we operate in a dynamic and challenging environment where fundamental research seamlessly transitions into drug discovery. Utilizing innovative technologies and advanced cell, organoid, and animal models, our aim is to develop novel humanized models for preclinical research. We are seeking a passionate PhD researcher to join our research team and contribute to the next steps of this investigation
Parkinson's disease and multiple system atrophy belong to a broader family of brain disorders characterized by glial and neurodegenerative pathologies. The exact etiology of these diseases remains unclear, but recent studies suggest that oligodendroglial cells may be early contributors to the disease process of these brain disorders.
As a PhD student, you will be responsible for developing innovative oligodendroglial humanized cell and animal models. You will work with human induced pluripotent stem cells, which will be further transplanted into mouse models via xenotransplantation. This approach will enable the study of the role of human cells in Parkinson's disease and multiple system atrophy.
This project offers a unique opportunity to contribute to cutting-edge research on the causes and treatments of neurodegenerative disorders, while developing your own skills and expertise in a stimulating research environment.
Keywords: Neurodegeneration, human pluripotent stem cells, xenotransplantation, alpha-synuclein, animal models, multiple system atrophy, Parkinson's disease
For more information please contact Prof. dr. Wouter Peelaerts, tel.: +32 16 37 40 59, mail: wouter.peelaerts@kuleuven.be.
KU Leuven strives for an inclusive, respectful and socially safe environment. We embrace diversity among individuals and groups as an asset. Open dialogue and differences in perspective are essential for an ambitious research and educational environment. In our commitment to equal opportunity, we recognize the consequences of historical inequalities. We do not accept any form of discrimination based on, but not limited to, gender identity and expression, sexual orientation, age, ethnic or national background, skin colour, religious and philosophical diversity, neurodivergence, employment disability, health, or socioeconomic status. For questions about accessibility or support offered, we are happy to assist you at this email address.
KU Leuven is an autonomous university. It was founded in 1425. It was born of and has grown within the Catholic tradition.
Visit the employer page