The Helmholtz Zentrum München in Munich, Germany, is member of one of the leading research associations in Europe - the Helmholtz Association of German Research Centers. The aim of our research is to proactively detect health risks involving humans and the environment, decoding the mechanisms of pathogenesis and developing concepts for prevention and therapy.
Adipose tissue is a central regulator of whole body metabolism with important endocrine function. To support our ongoing efforts in understanding the metabolic regulation through adipose tissue cell surface proteins, the Junior Research Group “Adipocytes and Metabolism” at the Helmholtz Zentrum München is seeking candidates to further develop and apply a method to screen for adipose tissue specific drug delivery vehicles. The proposed project is centered on an in vivo/ in vitro screen to identify fat specific DNA and or RNA aptamers, identification of individual sequences by next generation sequencing and the use of the identified aptamers for adipose selective drug delivery and to create a landscape of the adipose tissue cell surfome.
- PhD in biology, chemistry or a related field
- Analysis of next generation sequencing data
- Experience in establishing PCR protocols
- Familiarity with adipose tissue would be an advantage
- Knowledge in handling of mice would be ideal (preferably with FELASA-B certification)
- Good knowledge of standard molecular and biochemical methods to study protein-protein interactions and intracellular signaling cascades
- Fluent English is required
- Working in an innovative, well- equipped and scientifically stimulating surrounding
- Further training opportunities
- Initial short-term employment contract for two years with a standard public service salary (TV EntgO Bund, EG 13)
As German Research Center for Environmental Health, Helmholtz Zentrum München pursues the goal of developing personalized medical approaches for the prevention and therapy of major common diseases such as diabetes mellitus and lung diseases. Helmholtz Zentrum München is a member of the Helmholtz Association, Germany's largest scientific organization.
The Helmholtz Zentrum München as holder of the Bavarian Advancement of Women Prize and of the Total E-Quality Certificate is striving to increase the overall proportion of women on its staff and thus expressly urges qualified women to apply.
We are looking forward to receiving your comprehensive online application incl. cover letter, CV and references.
Dr. Siegfried Ussar
Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
NWG Adipocytes and Metabolism
Institute for Diabetes and Obesity